PD Dr. med. Dr. sc. nat. Stephan Winnik

Mitgliedschaften

• Schweizerische Gesellschaft für Kardiologie (SGK)
• Zürcher Gesellschaft für Kardiologie (ZGK)
• Europäische Gesellschaft für Kardiologie (ESC, Fellow)
• Europäische Herzinsuffizienz Vereinigung (HFA, Fellow)
• Europäische Herzrhythmus Vereinigung (EHRA)
• Ärztegesellschaft Zürcher Oberland (AGZO)
• Deutsche Gesellschaft für Kardiologie (DGK)
• Foedaratio Medicorum Helveticorum (FMH)
• Swiss MD/PhD Association

 

Aktuelle Lehrtätigkeit

• Vorlesung „Neue Entwicklungen in der Device-Therapie“ im Rahmen des Mantelstudiums „Neue Entwicklungen in der Kardiovaskulären Medizin“, Medizinische Fakultät, Universität Zürich
• Leitung klinischer Untersuchungskurse in Innerer Medizin für Studenten der Medizin der Universität Zürich (3. und 5. Studienjahr), bis 2021 am Universitätsspital Zürich, seit 2021 am GZO Spital Wetzikon
• Professionsübergreifende Weiterbildung als Instruktor für Advanced Cardiac Life Support (ACLS)
• Weiterbildung nationaler und internationaler kardiologischer Fachärzte im Rahmen des Postgraduate Course in Heart Failure (PCHF), eines Kurses der Europäischen Gesellschaft für Kardiologie und der European Heart Academy in Kollaboration mit der Universität Zürich (Certificate of Advanced Studies)
• Betreuung von Masterstudentinnen und -Studenten sowie Doktorandinnen und Doktoranden der Medizinischen bzw. Mathematisch Naturwissenschaftlichen Fakultät der Universität Zürich

 

Experten- und Forschungstätigkeit

• Leitung der Arbeitsgruppe CIED/CRT
• National Principle Investigator AMEND-CRT (NCT04225520)
• Associate Editor / Editorial Board, European Heart Journal
• Gutachter für diverse Fachzeitschriften (Auswahl): Annals of Internal Medicine, European Heart Journal, Cardiovascular Research, European Journal of Clinical Investigation, Journal of Heart and Lung Transplantation
• Schweizerische Arbeitsgruppe Herzinsuffizienz
• Schweizerische Arbeitsgruppe Rhythmologie

 

Preise und Auszeichnungen

• 2019: Fellow Europäische Herzinsuffizienz Vereinigung (FHFA)
• 2018: Fellow Europäische Gesellschaft für Kardiologie (FESC)
• 2015: Otto Hess Trainee Award, Schweizerische Gesellschaft für Kardiologie (SGK)
• 2010: Best Oral Presentation Award, 16^. Cardiovascular Research & Clinical Implications Meeting Schweizerische Gesellschaft für Kardiologie (SGK)
• 2009: Experimentelle Promotion, summa cum laude, Universität Freiburg i.Br.
• 2007: Stipendium, Dr. Heinrich Kircher Stiftung, Forschungsaufenthalt, McAllister Heart Institute, University of North Carolina, Chapel Hill, NC, USA
• 1999: Vollstipendium ASSIST (American Secondary Schools for International Students and Teachers), St. Mark’s School of Texas, Dallas, TX, USA

 

Ausserdem

• Sprachen: Deutsch, Englisch, Französisch
• Verheiratet, Vater von 2 Töchtern
• Interessen: Segeln, Radsport, Fotographie

 

Publikationen

Challenges and Pitfalls during CRT Implantation in Patients with Persistent Left Superior Vena Cava. Akdis D, Vogler J, Sieren M, Molitor N, Sasse, T, Phan HL, Bartoli L, Grosse N, Saguner A, Eriksson U, Duru F, Hofer D, Breitenstein A, Tilz R, Winnik S. Journal of Interventional Cardiac Electrophysiology. Jan 2024 (accepted)

 

Long-term outcome after upgrade to cardiac resynchronization therapy: A propensity score-matched analysis. Trenson S, Voros G, Martens P, Ingelaere S, Betschart P, Voigt JU, Dupont M, Breitenstein A, Steffel J, Willems R, Ruschitzka F, Mullens W, Vandenberk B*., Winnik S*. Eur J Heart Fail. 2023 Oct 31. doi: 10.1002/ejhf.3073

 

Evolution and triggers of defibrillator shocks in patients with arrhythmogenic right ventricular cardiomyopathy. Molitor N, Hofer D, Çimen T, Gasperetti A, Akdis D, Costa S, Jenni R, Breitenstein A, Wolber T, Winnik S, Fokstuen S, Fu G, Medeiros-Domingo A, Ruschitzka F, Brunckhorst C, Duru F, Saguner AM. Heart. 2023 Jul 12;109(15):1146-1152. doi: 10.1136/heartjnl-2022-321739

 

Transesophageal Echocardiography-Guided Transseptal Left Atrial Access to Improve Safety in Patients Undergoing Pulmonary Vein Isolation. Zuercher R, Herling A, Schmidt MT, Bachmann M, Winnik S, Duru F, Eriksson U. J Clin Med. 2022 May 1;11(9):2546. doi: 10.3390/jcm11092546

 

Right ventricular only pacing for cardiac resynchronization therapy. Hermes-Laufer J, Hofer D, Flammer A, Ruschitzka F, Steffel J, Winnik S. Europace. 2022 Jan 4;24(1):70-71. doi: 10.1093/europace/euab145

 

MitraClip^® procedure as bridge to left ventricular assist device: Enable extracorporeal membrane oxygenation weaning and reduce perioperative risk. Schmiady MO, Winnik S, Bettex D, Aser R. Perfusion. 2022 Jan 3. Online ahead of print. doi: 10.1177/02676591211065251

 

The novel TRPM4 c.448G>T variant is associated with familial conduction disorders, cardiomyopathy, and sudden cardiac death. Winnik S*, Kovacs B*, Medeiros-Domingo A, Costa S, Fu G, Biskup S, Ruschitzka F, Flammer AJ, Tanner FC, Duru F, Saguner AM. Cardiol J. 2022;29(3):514-516. doi: 10.5603/CJ.a2021.0157

 

Heart Failure in COVID-19: the multicenter, multinational PCHF-COVICAV registry. Sokolski M, Trenson S, Sokolska JM, D'Amario D, Meyer P, Poku NK, Biering-Sørensen T, Højbjerg Lassen MT, Skaarup KG, Barge-Caballero E, Pouleur A-C, Stolfo D, Sinagra G, Ablasser K, Muster V, Rainer PP, Wallner M, Chiodini A, Heiniger PS, Mikulicic F, Schwaiger J, Winnik S, Cakmak H, Gaudenzi M, Mapelli M, Mattavelli I, Paul M, Cabac-Pogorevici I, Bouleti C, Lilliu M, Minoia C, Dauw J, Costa J, Celik A, Mewton N, Montenegro CEL, Matsue Y, Loncar G, Marchel M, Bechlioulis A, Michalis L, Dörr M, Prihadi E, Schoenrath F, Messroghli DR, Mullens W, Lund LH, Rosano GMC, Ponikowski P, Ruschitzka F, Flammer AJ. ESC Heart Failure 2021 Dec;8(6):4955-4967. doi: 10.1002/ehf2.13549. Epub 2021 Sep 17

 

Heart Failure Association of the ESC position paper on the management of LVAD supported patients for the non LVAD specialist healthcare provider Part 1: Introduction and at the non-hospital settings in the community. Ben Avraham B, Crespo-Leiro MG, Filippatos G, Gotsman I, Seferovic P, Hasin T, Potena L, Milicic D, Coats AJS, Rosano G, Ruschitzka F, Metra M, Anker S, Altenberger J, Adamopoulos S, Barac YD, Chioncel O, De Jonge N, Elliston J, Frigeiro M, Goncalvesova E, Grupper A, Hamdan R, Hammer Y, Hill L, Itzhaki Ben Zadok O, Abuhazira M, Lavee J, Mullens W, Nalbantgil S, Piepoli MF, Ponikowski P, Ristic A, Ruhparwar A, Shaul A, Tops LF, Tsui S, Winnik S, Jaarsma T, Gustafsson F, Ben Gal T. ESC Heart Fail. 2021 Dec;8(6):4394-4408. doi: 10.1002/ehf2.13588. Epub 2021 Sep 14

 

Heart Failure Association of the ESC position paper on the management of left ventricular assist device-supported patients for the non-left ventricular assist device specialist healthcare provider: Part 2: at the emergency department. Milicic D, Ben Avraham B, Chioncel O, Barac YD, Goncalvesova E, Grupper A, Altenberger J, Frigeiro M, Ristic A, De Jonge N, Tsui S, Lavee J, Rosano G, Crespo-Leiro MG, Coats AJS, Seferovic P, Ruschitzka F, Metra M, Anker S, Filippatos G, Adamopoulos S, Abuhazira M, Elliston J, Gotsman I, Hamdan R, Hammer Y, Hasin T, Hill L, Itzhaki Ben Zadok O, Mullens W, Nalbantgil S, Piepoli MF, Ponikowski P, Potena L, Ruhparwar A, Shaul A, Tops LF, Winnik S, Jaarsma T, Gustafsson F, Ben Gal T. ESC Heart Fail. 2021 Dec;8(6):4409-4424. doi: 10.1002/ehf2.13587. Epub 2021 Sep 14

 

Heart Failure Association of the ESC position paper on the management of LVAD-supported patients for the non-LVAD specialist healthcare provider Part 3: at the hospital and discharge. Gustafsson F, Ben Avraham B, Chioncel O, Hasin T, Grupper A, Shaul A, Nalbantgil S, Hammer Y, Mullens W, Tops LF, Elliston J, Tsui S, Milicic D, Altenberger J, Abuhazira M, Winnik S, Lavee J, Piepoli MF, Hill L, Hamdan R, Ruhparwar A, Anker S, Crespo-Leiro MG, Coats AJS, Filippatos G, Metra M, Rosano G, Seferovic P, Ruschitzka F, Adamopoulos S, Barac Y, De Jonge N, Frigerio M, Goncalvesova E, Gotsman I, Itzhaki Ben Zadok O, Ponikowski P, Potena L, Ristic A, Jaarsma T, Ben Gal T. ESC Heart Fail. 2021 Dec;8(6):4425-4443. doi: 10.1002/ehf2.13590. Epub 2021 Sep 28

 

Guidance on the management of left ventricular assist device (LVAD) supported patients for the non-LVAD specialist healthcare provider: executive summary. Ben Gal T, Ben Avraham B, Milicic D, Crespo-Leiro MG, Coats AJS, Rosano G, Seferovic P, Ruschitzka F, Metra M, Anker S, Filippatos G, Altenberger J, Adamopoulos S, Barak Y, Chioncel O, de Jonge N, Elliston J, Frigerio M, Goncalvesova E, Gotsman I, Grupper A, Hamdan R, Hammer Y, Hasin T, Hill L, Itzhaki Ben Zadok O, Abuhazira M, Lavee J, Mullens W, Nalbantgil S, Piepoli MF, Ponikowski P, Potena L, Ristic A, Ruhparwar A, Shaul A, Tops LF, Tsui S, Winnik S, Jaarsma T, Gustafsson F. Eur J Heart Fail. 2021 Oct;23(10):1597-1609. doi: 10.1002/ejhf.2327. Epub 2021 Aug 22

 

Treatment of Advanced Heart Failure-Focus on Transplantation and Durable Mechanical Circulatory Support: What Does the Future Hold? Guidetti F, Arrigo M, Frank M, Mikulicic F, Sokolski M, Aser R, Wilhelm MJ, Flammer AJ, Ruschitzka F, Winnik S. Heart Fail Clin. 2021 Oct;17(4):697-708

 

Left femoral venous access for leadless pacemaker impantation: patient characteristics and outcome. Jelisejevas J, Breitenstein A, Hofer D, Winnik S, Steffel J, Saguner AM. Europace 2021 Sep 8;23(9):1456-1461. doi: 10.1093/europace/euab083

 

Transvenous Lead Extraction in a Patient with Persistent Left Superior Vena Cava. Trenson S, Doering M, Hindricks G, Richter S*, Winnik S*. HeartRhythm Case Reports. 2020 Dec 10

 

Takotsubo Syndrome in Coronvirus Disease 2019. Templin C, Manka R, Cammann VL, Szawan KA, Gotschy A, Karolyi M, Winnik S, Moch H, Meyer P, Moreo A, Bossone E, D'Ascenzo F, Secco GG, Mancone M, Infusino F, Gaido L, Giammaria M, Wittstein IS, Varga Z, Ghadri JR. Am J Cardiol. 2021 Jan 1;138:118-120. doi: 10.1016/j.amjcard.2020.10.005. Epub 2020 Oct 9

 

Differential effect of cardiac resynchronization therapy in patients with diabetes mellitus: a long-term retrospective cohort study. Kahr PC, Trenson S, Schindler M, Kuster J, Kaufmann P, Tonko J, Hofer D, Inderbitzin DT, Breitenstein A, Saguner AM, Flammer AJ, Ruschitzka F, Steffel J, Winnik S. ESC Heart Fail. 2020 Oct;7(5):2773-2783

 

Endomyocardial Biopsy-Induced Coronary-Cameral Fistula. Trenson S, Hofer D, Sokolski M, Mikulicic F, Ruschitzka F, Flammer AJ, Winnik S. Cardiology and Cardiovascular Medicine. 2020 Oct; 4(5): 620-622

 

Long-term follow-up after cardiac resynchronization therapy-optimization in a real-world setting: A single-center cohort study. Korach R, Kahr PC, Ruschitzka F, Steffel J, Flammer AJ*, Winnik S*. Cardiol J. 2021;28(5):728-737. doi: 10.5603/CJ.a2020.0004. Epub 2020 Jan 21

 

Pulsatile arterial blood pressure mimicking aortic valve opening during continuous-flow LVAD support: a case report. Paprotny M, Ruschitzka F, Lüders B, Wilhelm MJ, Aser R, Bettex D, Flammer AJ, Rudiger A, Winnik S. J Cardiothorac Surg. 2019 Dec 18;14(1):219

 

Right Ventricular Failure: Pathophysiology, Diagnosis and Treatment. Arrigo M, Huber LC, Winnik S, Mikulicic F, Guidetti F, Frank M, Flammer AJ, Ruschitzka F. Card Fail Rev. 2019 Nov 4;5(3):140-146

 

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry. Sawhney JP, Kothiwale VA, Bisne V, Durgaprasad R, Jadhav P, Chopda M, Vanajakshamma V, Meena R, Vijayaraghavan G, Chawla K, Allu J, Pieper KS, John Camm A, Kakkar AK; GARFIELD-AF Investigators. Indian Heart J. 2018 Nov;70(6): 828-835

 

The effect of oxygen in Sirt3-mediated myocardial protection: a proof-of-concept study in cultured cardiomyoblasts. Diehl P, Gaul DS, Sogl J, Flierl U, Henstridge D, Pahla J, Bugger H, Emmert MY, Ruschitzka F, Bode C, Lüscher TF, Moser M, Matter CM, Peter K, Winnik S. J Thromb Thrombolysis. 2018 Jul;46(1):102-112

 

Usefulness of a clinical risk score to predict the response to cardiac resynchronization therapy. Providencia R, Marijon E, Barra S, Reitan C, Breitenstein A, Defaye P, Papageorgiou N, Duehmke R, Winnik S, Ang R, Klug D, Gras D, Oezkartal T, Segal OR, Deharo JC, Leclercq C, Lambiase PD, Fauchier L, Bordachar P, Steffel J, Sadoul N, Piot O, Borgquist R, Agarwal S, Chow A, Boveda S; DAI-PP Investigators. Int J Cardiol. 2018 Jun 1;260:82-87

 

Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity. Gaul DS, Weber J, van Tits LJ, Sluka S, Pasterk L, Reiner MF, Calatayud N, Lohmann C, Klingenberg R, Pahla J, Vdovenko D, Tanner FC, Camici GG, Eriksson U, Auwerx J, Mach F, Windecker S, Rodondi N, Lüscher TF, Matter CM*, Winnik S*. Cardiovasc Res. 2018 Jul 1; 114(8):1178-1188

 

SAVE-AMD: Safety of VEGF Inhibitors in Age-Related Macular Degeneration. Enseleit F, Michels S, Sudano I, Stahel M, Zweifel S, Schlager O, Becker M, Winnik S, Nägele M, Flammer AJ, Neidhart M, Graf N, Matter CM, Seifert B, Lüscher TF, Ruschitzka F. Ophthalmologica. 2017;238(4):205-216

 

"Real world” experience in Cardiac Resynchronization Therapy at a Swiss Tertiary Care Center. Winnik S. Elsener C, Seifert B, Starck C, Straub A, Saguner AM, Breitenstein A, Krasniqi N, Wilhelm MJ, Haegeli L, Duru F, Benussi S, Maisano F; Lüscher TF, Holzmeister J, Huerlimann D, Rischitzka F, Steffel J. Swiss Med Wkly. 2017 Apr 19;147:14425

 

Brain-Derived Neurotrophic Factor Val66Met Polymorphism in Depression and Thrombosis: SIRT1 as a Possible Mediator. Stein S, Winnik S, Matter CM. Eur Heart J 2017, 38(18): 1436–38

 

Successful cryoablation of an anteroseptal accessory pathway guided by electroanatomical activation mapping. Yalcinkaya E, Winnik S, Haegeli L, Brunckhorst C, Duru F. J Invasive Cardiol.  2016 Dec;28(12):E227

 

Comparison of international normalized ratio audit parameters in patients enrolled in GARFIELD-AF and treated with vitamin K antagonists. Fitzmaurice DA, Accetta G, Haas S, Kayani G, Lucas Luciardi H, Misselwitz F, Pieper K, Ten Cate H, Turpie AG, Kakkar AK; GARFIELD-AF Investigators. Br J Haematol. 2016 Aug;174(4):610-23

 

Mild endotherlial dysfunction in Sirt3 knockout mice fed a high-cholsterol diet - protective role fo a novel C/EBP-ß-dependent feedback regulation of SOD2. Winnik S, Gaul DS, Siciliani G, Lohmann C, Pasterk L, Calatayud N, Weber J, Eriksson U, Auwerx J, van Tits LJ, Lüscher TF, Matter CM. Basic Res Cardiol 2016, May;111(3)33

 

AV block on exertion – pulmonary sarcoidosis with involvement of the His-Purkinje System. Winnik S, Lüscher T.F., Herzog B., Haegeli L. Am J Med. 2015 Dec;128(12):e31-3

 

Protective effects of sirtuins in cardiovascular diseases - from bench to bedside. Winnik S, Auwerx J, Sinclair DA, Matter CM. Eur Heart J. 2015;36 (48): 3404–12

 

The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression. Miranda MX, van Tits LJ, Lohmann C, Arsiwala T, Winnik S, Tailleux A, Stein S, Gomes AP, Suri V, Ellis JL, Lutz TA, Hottiger MO, Sinclair DA, Auwerx J, Schoonjans K, Staels B, Lüscher TF, Matter CM. Eur Heart J. 2015 Jan 1;36(1):51-59

 

Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL recpetor knock-out mice: Implications for cardiovascular risk factor development. Winnik S, Gaul DS, Preitner F, Lohmann C, Weber J, Miranda MX, Liu Y, van Tits LJ, Mateos JM, Brokopp CE, Auwerx J, Thorens B, Lüscher TF, Matter CM. Basic Res Cardiol. 2014 Jan;109(1):399

 

The wealth of nations and the dissemination of cardiovascular research. Winnik S, Speer T, Raptis DA, Walker JH, Hasun M, Clavien PA, Komajda M, Bax JJ, Tendera M, Fox K, Van de Werf F, Mundow C, Lüscher TF, Ruschitzka F, Nallamothu BK, Matter CM. In J Cardiol. 2013 Nov 05;169(3):190-5

 

Multimodal imaging in rats reveals impaired neurovascular coupling in sustained hypertension. Calcinaghi N, Wyss MT, Jolivet R, Singh A, Keller, AL, Winnik S, Fritschy J-M, Buck A, Matter CM, Weber B: Stroke. 2013 Jul;44(7):1957-64

 

Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity. Schäfer N, Lohmann C, Winnik S, van Tits LJ, Miranda MX, Vergopulos A, Ruschtizka F, Nussberger J, Berger S, Lüscher TF, Verrey F, Matter CM. Eur Heart J. 2013 Dec; 34(45):3515-24

 

Abnormal High-Density Lipoprotein Induces Endtohelial Dysfunction via Activation of Toll-Like Receptor-2. Speer T, Rohrer L, Blyszczuk P, Shroff R, Kuschnerus K, Kränkel N, Kania G, Zewninger S, Akhmedov A, Shi Y, Martin T, Perisa D, Winnik S, Müller MF, Sester U, Wernicke G, Jung A, Gutteck U, Eriksson U, Geisel J, Deanfiels J, von Eckardstein A, Lüscher TF, Fliser D, Bahlmann FH, Landmesser U. Immunity. 2013 April 18;38(4):754-768

 

Systemic VEGF inhibition accelerates experimental atherosclerosis and disrupts endothelial homeostasis – implications for cardiovascular safety. Winnik S, Lohmann C, Siciliani G, von Lucowicz T, Kuschnerus K, Kraenkel N, Brokopp CE, Enseleit F, Michels S, Lüscher TF, Matter CM. Int J Cardiol. 2013 Oct 3;168(3):2453-2461

 

Letter in Response to “Conversion of Cardiovascular Conference Abstracts to Publications” published in Circulation 2012 vol. 126(24) pp. 2819-2825. Winnik S, Lüscher TF, Matter CM. Circ. 2013 Jul 2;128(1):e9

 

Exacerbation of chronic lower back pain with an unexpected twist. Winnik S, Hitz A, Wyden S, Peter U, Eriksson U, Stieger R: Praxis. 2013 Jun 5;102(12):747-750

 

Sirt1 an anti-inflammatory pathway at the crossroads between metabolic disease and atherosclerosis. Winnik S, Stein S, Matter CM. Current Vascular Pharmacol. 2012;10(6): 693-696

 

From Abstract to Impact in Cardiovascular Science – Factors Predicting Publication and Citation. Winnik S, Raptis DA, Walker JH, Hasun M, Speer T, Clavien P-A, Komajda M, Bax JJ, Tendera M, Fox K, Van de Werf F, Mundow C, Lüscher TF, Matter CM. Eur Heart J. 2012; 33(24): 3034-3045

 

Lack of association between connexin 40 polymorphisms and coronary artery disease. Pfenniger A, van der Laan SW, Foglia B, Dunoyer-Geindre S, Haefliger JA, Winnik S, Mach F, Pasterkamp G, James RW, Kwak BR. Atherosclerosis. 2012;222(1):148-153

 

Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study. Enseleit F, Sudano I, Périat D, Winnik S, Wolfrum M, Flammer AJ, Fröhlich GM, Kaiser P, Hirt A, Haile SR, Krasniqi N, Matter CM, Uhlenhut K, Högger P, Neidhart M, Lüscher TF, Ruschitzka F, Noll G. Eur Heart J. 2012;33(13):1589-1597

 

Fibroblast Activation Protein is Induced by Inflammation and Degrades Type I Collagen in Thin-Cap Fibroatheromata. Brokopp CE, Schoenauer R, Richards P, Bauer S, Lohmann C, Emmert MY, Weber B, Winnik S, Aikawa E, Graves K, Genoni M, Vogt P, Lüscher TF, Renner C, Hoerstrup SP*, Matter CM*. Eur Heart J. 2011 Nov;32(21):2713-2722

 

Alpha-Linolensäure in der kardiovaskulären Prävention? Winnik S, Beer JH, Matter CM. Leading Opinions, Kardiologie & Gefässmedizin. 2011 Feb

 

Plasma RANTES – a molecular fingerprint of the unstable plaque? Winnik S, Klingenberg R, Matter CM. Eur Heart J. 2011 Feb;32(4):393-295

 

Dietary alpha-linolenic acid (ALA) diminishes experimental atherogenesis and restricts T cell-driven inflammation. Winnik S, Lohmann C, Richter EK, Schäfer N, Song W-L, Leiber F, Mocharla P, Hofmann J, Klingenberg R, Borén J, Becher B, FitzGerald GA, Lüscher TF, Matter CM*, Beer JH*. Eur Heart J. 2011 Oct;32(20):2573-2584

 

Recombinant interleukin-11 treatment enhances collateral vessel growth after femoral artery ligation. Aitsebaomo J, Srivastava S, Zhang H, Jha S, Wang Z, Winnik S, Valava AN, Pi X, Lockyer P, Faber JE, Patterson C. Atherscler Thromb Vasc Biol. 2011 Feb;31(2):306-312

 

SIRT1 reduces endothlial activation without affecting vascular function in ApoE-/- mice. Stein S, Schäfer N, Breitenstein A, Besler C, Winnik S, Lohmann C, Heinrich K, Brokopp CE, Handschin C, Landmesser U, Tanner FC, Lüscher TF, and Matter CM. Aging (Albany NY). 2010 Jun;2(6):353-360

 

HoxB5 induces both sprouting and intussusceptive angiogenesis in an Angiopoietin-2 (Ang2) dependent manner. Winnik S, Kurz H, Klinkert M, Zoeller C, Augustin H, Wu Y, Bode C, Patterson C, Moser M. Cardiovasc Res. 2009 Aug 1;83(3): 558-565

 

ERK signaling is a central regulator for BMP-4 dependent capillary sprouting. Zhou Q, Heinke J, Vargas A, Winnik S, Krauss T, Bode C, Patterson C, Moser M. Cardiovasc Res. 2007 Dec 1;76(3): 390-399